That was my take as well since it appears to be Linux based, but of course whatever you plug in would need an app that utilizes the hardware to make it useful unless it was some form of input device like a keyboard or mouse.My guess is that if the device works out of the box in linux, it will work in ChromeOS. If I had a CR48 I'd be doing ctrl-alt-t every day (http://www.chromebookforum.com/forum/14-google-cr-48-forum/217-crosh-shell.html).