I'm having a difficult time because I can't get my HTC Thunderbolt to synch with Outlook. It's kind of important to me and got me thinking. Can you synch a Chromebook to Outlook? Or use it with it, or whatever?
Outlook is an email client for windows, but your question depends on what your email server is, as Outlook will work with gmail, hotmail, Exchange, etc.
Chromebooks use gmail or other web based email clients. For most email servers this is no problem, but if your corporate email uses Exchange then you will need to point your browser at an 'outlook web access' (owa) site.